Mr. Keaney is a senior executive with over 25 years of experience managing biotechnology companies from the start-up phase through periods of rapid growth into complex publicly traded entities.  He is experienced in building systems and infrastructure, successful at fundraising, and has been integral in the process of three IPOs.  Bryan has served in senior roles at CombinatoRx, Inc., Synta Pharmaceuticals Corp., Shionogi Bioresearch Corp., held a variety of management roles at Genzyme Corporation and Hybritech Inc.